When Meng Ze Ming found out that he inherited Spinocerebellar degeneration from his father, a progressive genetic disease that would eventually rob him of his eye sight, his memory, his ability to move, he decided to use whatever time he has left to build a green building as a home base to promote forest preservation. As his dream turns into reality, he also comes to term with his disease.

見到登山社長孟澤銘（王傳一 飾）的第一眼，何萱（李千娜 飾）就差點氣喘發作了。為了追逐她「命中注定」的愛情，何萱冒著氣喘的風險，追隨澤銘攀登了兩座台灣百岳，來到傳說中「天使的眼淚」——南橫的嘉明湖；終於， 在「天使的眼淚」裡，小女子實現了愛情的心願，與澤銘約定：此生契闊、 永遠相守。愛山的澤銘，即將從建築研究所畢業；他懷有許多偉大的夢想，其中「藍屋頂」是所有夢想的核心—這將是一棟綠建築、也將是推廣山林保育的基地。就在何萱與澤銘開始打造「藍屋頂」的夢想時，澤銘卻罹患了怪病，他漸漸無法控制自己的肢體，視線也變得模糊起來……澤銘的母親黎鳳蓮(劉瑞琪 飾)，是一個個性堅韌、頗負盛名的教育專欄作家。過去， 她一直以為丈夫是意外身亡；但如今，大兒子的怪病讓她明白：原來丈夫的家族藏有「小腦萎縮症」的基因，而長子澤銘不幸遺傳到此基因。